Verrucous Carcinoma of the Uterine Cervix Arising in a Giant Condyloma Acuminatum, Associated with Ichthyosis of the Endometrial Cavity

We describe a unique presentation of cervical verrucous carcinoma (VC) associated with ichthyosis the uterine cavity in an 80-year old woman. Areas transition from giant condyloma (GC) were present VC. This paper also includes review relevant literature. VC cervix is uncommon malignancy, and GC to interesting finding, confuting theory that they represent distinct entities, different risk factors. Differently GC, considered be causally related HPV minority instances. Our results p16 immunohistochemistry, surrogate marker high-risk human papillomavirus (HPV) infection, appear speak against causal role pathogenesis Ichthyosis uteri may occasionally or endometrial malignancy; however, we are not aware any patient showing VC, at same time.